Terry45, this is only the beginning of the "rabbit hole" it gets deep pretty quick! There are a ton of options and exploring them is half the fun. I rebuilt a MIM strat years ago but decided to go the Little 59 & JB Jr. route. . .that's what worked for me. . . pretty sweet set up too, loved it! PUPs will make a difference but it can be more subtle than say playing through a different amp. Remember it has to sound good to you, that's the most important part. Finding that tone that makes you want to play. . . .priceless!!